Several user examples are available directly in Geant4 for the usage of Geant4-DNA processes and models. These examples are located in the $G4INSTALL/examples directory of the Geant4 installation. A README file is provided with each example directly in their source directory.

We will also provide soon Geant4-DNA user applications in
GitHub.

Physics

  • The « dnaphysics » extended/medical/dna example illustrates how to use Geant4-DNA Physics processes and models. It also shows how to extract physical information at the step level, such as process type, position and energy deposited and how to use the variable density material feature for liquid water.

  • The « microdosimetry » extended/medical/dna example shows how to combine Geant4 Standard electromagnetic Physics processes and models with Geant4-DNA Physics processes and models in two regions filled with liquid water, illustrating the combination of condensed history and discrete processes at different scales.

  • The « range » extended/medical/dna example explains how to extract ranges.

  • The « clustering » extended/medical/dna example illustrates how to identify ionisation clusters.

  • The « svalue » extended/medical/dna example explains how to simulate S-values in spherical targets of liquid water.

  • The « wvalue » extended/medical/dna example explains how to simulate w-values in liquid water.

  • The « TestEm12 » extended/electromagnetic example explains how to extract radial dose distributions in spherical shells of liquid water (such as dose point kernels), using the dna.mac macro file.

Chemistry

  • The « chem1 » extended/medical/dna example illustrates how to activate the simulation of water radiolysis.

  • The « chem2 » extended/medical/dna example illustrates how to set minimum time step limits.

  • The « chem3 » extended/medical/dna example illustrates how to implement user actions in the chemistry module.

  • The « chem4 » extended/medical/dna example illustrates how to compute radiochemical yields.


Geometry

  • The Geant4 « wholeNuclearDNA » extended/medical/dna example shows how to model a cellular nucleus containing a geometrical model for the DNA molecule.

fig

  • The Geant4 « pdb4dna » extended/medical/dna example shows how to model molecular geometries from the Protein Data Bank (PDB) and record energy deposition events in biological volumes of interest. It is further described at http://pdb4dna.in2p3.fr.


1ZBB_Phys


  • The Geant4 « microbeam » advanced example explains how to define a realistic cellular phantom based on confocal microscopy imaging for the simulation of cellular irradiation in single ion mode, based on the CENBG microbeam irradiation facility.

Phantom


  • A short guide on how DNA geometries may be modelled in Geant4 is available here, written by Nathanael Lampe.

cut-ellipsoids-geant


Tutorials

We regularly present Geant4-DNA developments during official Geant4 tutorials. The following tutorials include a session dedicated to Geant4-DNA:

  • 2017 : Belgrade, Serbia (tbc)
  • 2016 : Belgrade, Serbia - October 28
  • 2015 : Hiroshima, Japan - August 23-24
  • 2014 : European Space Agency, Noordwijk, The Netherlands, November 7
  • 2013 : Bordeaux, France - October 10-11
  • 2013 : Wollongong University, Australia - April 19-24
  • 2012 : Jefferson Lab, VA, USA - July 9-13
  • 2011 : Karlsruhe Institute of Technology, Germany - October 25-26
  • 2011 : Texas A&M, TX, USA - January 10-14

IMG_3125IMG_4701Cv2N3vmVMAEGXdl
Left to right: ESA/ESTEC (2014), Hiroshima (2015), Belgrade (2016)



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